STD Rates in St. Louis County, Missouri

2023 CDC surveillance data for St. Louis County, Missouri — chlamydia, gonorrhea, and syphilis rates with state comparisons.

Data Year: 2023 Source: CDC STI Surveillance Population: 987,093
Combined
946
per 100K
5th / 115
Chlamydia
635.3
per 100K • 6,271 cases
US rate: 490.7
5th of 115 in Missouri
Higher than 87% of US counties
Gonorrhea
294.7
per 100K • 2,909 cases
US rate: 178.2
4th of 115 in Missouri
Higher than 92% of US counties
Syphilis P&S
16
per 100K • 158 cases
US rate: 15.8
34th of 115 in Missouri
Higher than 74% of US counties

St. Louis County has one of the higher STD burdens in Missouri, with a combined rate of 946.0 per 100,000 residents in 2023 — ranking 5th of 115 counties. Reported infections included chlamydia at 635.3 per 100,000 (6,271 cases, 27% above the state rate), gonorrhea at 294.7 per 100,000 (2,909 cases, 46% above the state rate), syphilis at 16.0 per 100,000 (158 cases, 26% below the state rate). Routine testing is the surest way to catch STDs early, since many produce no symptoms. St. Louis County has confidential testing locations available.

STD Trends in St. Louis County, 2000–2023

Reported cases per 100,000 residents each year, against the Missouri rate (dashed). In a county this size a handful of cases moves the rate a long way, so read the shape rather than any single year.

Chlamydia
635.3
per 100K in 2023
244.9 in 2000
Peak 663.7 in 2019
Gonorrhea
294.7
per 100K in 2023
171.0 in 2000
Peak 339.5 in 2020
Syphilis (P&S)
16.0
per 100K in 2023
1.2 in 2000
Peak 18.4 in 2021

Source: CDC NCHHSTP AtlasPlus county surveillance, 2000–2023.

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St. Louis County vs Missouri and the US

Infection St. Louis County Missouri US vs Missouri vs US Rank in Missouri
Chlamydia 635.36,271 cases 498.6 490.7 27.4% above 29.5% above 5th of 115
Gonorrhea 294.72,909 cases 201.9 178.2 46% above 65.4% above 4th of 115
Syphilis (P&S) 16158 cases 21.5 15.8 25.6% below 1.3% above 34th of 115

Rates per 100,000 residents, 2023. Ranks run from the highest rate (1st) among Missouri’s counties. The US rate is all 50 states combined. Comparisons are left out where fewer than 20 cases were reported, because a rate built on so few cases can swing widely from one year to the next.

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FAQs

St. Louis County ranks 5th of 115 Missouri counties for combined STD rate in 2023, at 946.0 per 100,000 residents.
In 2023, chlamydia was the most frequently reported STD in St. Louis County, with 6,271 cases at a rate of 635.3 per 100,000 residents.
STDTest.com lists confidential testing locations across St. Louis County and Missouri. Many offer same-day appointments with results in 1–3 days.
Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.