STD Rates in St. Louis City, Missouri

2023 CDC surveillance data for St. Louis City, Missouri — chlamydia, gonorrhea, and syphilis rates with state comparisons.

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Data Year: 2023 Source: CDC STI Surveillance Population: 281,751
Combined
2201.6
per 100K
1st / 115
Chlamydia
1340.9
per 100K • 3,778 cases
Gonorrhea
809.9
per 100K • 2,282 cases
Syphilis P&S
50.8
per 100K • 143 cases

St. Louis City has one of the higher STD burdens in Missouri, with a combined rate of 2,201.6 per 100,000 residents in 2023 — ranking 1st of 115 counties. Reported infections included chlamydia at 1340.9 per 100,000 (3,778 cases, 169% above the state rate), gonorrhea at 809.9 per 100,000 (2,282 cases, 301% above the state rate), syphilis at 50.8 per 100,000 (143 cases, 136% above the state rate). Many STDs show no symptoms, so testing is the only reliable way to know your status. Confidential options are available across St. Louis City.

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St. Louis City vs Missouri Average

Infection St. Louis City Missouri Rate Difference
Chlamydia 1340.9 498.6 169% above
Gonorrhea 809.9 201.9 301% above
Syphilis (P&S) 50.8 21.5 136% above

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Largest Counties in Missouri

St. Louis County → Jackson County → St. Charles County → Greene County → Clay County → Jefferson County → Boone County → Jasper County → Platte County → Cass County →

All 115 Missouri counties → STD testing in Missouri →

FAQs

St. Louis City ranks 1st of 115 Missouri counties for combined STD rate in 2023, at 2,201.6 per 100,000 residents.
In 2023, chlamydia was the most frequently reported STD in St. Louis City, with 3,778 cases at a rate of 1340.9 per 100,000 residents.
STDTest.com lists confidential testing locations across St. Louis City and Missouri. Many offer same-day appointments with results in 1–3 days.

Related Resources

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Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.
Sources