STD Rates in San Mateo County, California

2023 CDC surveillance data for San Mateo County, California — chlamydia, gonorrhea, and syphilis rates with state comparisons.

Data Year: 2023 Source: CDC STI Surveillance Population: 726,415
Combined
494.9
per 100K
25th / 58
Chlamydia
360.4
per 100K • 2,618 cases
US rate: 490.7
26th of 58 in California
Higher than 64% of US counties
Gonorrhea
125.3
per 100K • 910 cases
US rate: 178.2
17th of 58 in California
Higher than 71% of US counties
Syphilis P&S
9.2
per 100K • 67 cases
US rate: 15.8
41st of 58 in California
Higher than 58% of US counties

San Mateo County reported a combined STD rate of 494.9 per 100,000 residents in 2023, placing it 25th of 58 California counties — in the upper half of the state. Reported infections included chlamydia at 360.4 per 100,000 (2,618 cases, 27% below the state rate), gonorrhea at 125.3 per 100,000 (910 cases, 34% below the state rate), syphilis at 9.2 per 100,000 (67 cases, 44% below the state rate). Many STDs show no symptoms, so testing is the only reliable way to know your status. Confidential options are available across San Mateo County.

STD Trends in San Mateo County, 2000–2023

Reported cases per 100,000 residents each year, against the California rate (dashed). In a county this size a handful of cases moves the rate a long way, so read the shape rather than any single year.

Chlamydia
360.4
per 100K in 2023
0.0 in 2000
Peak 416.0 in 2019
Gonorrhea
125.3
per 100K in 2023
0.0 in 2000
Peak 125.3 in 2023
Syphilis (P&S)
9.2
per 100K in 2023
0.1 in 2000
Peak 12.5 in 2022

Source: CDC NCHHSTP AtlasPlus county surveillance, 2000–2023.

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San Mateo County vs California and the US

Infection San Mateo County California US vs California vs US Rank in California
Chlamydia 360.42,618 cases 491.1 490.7 26.6% below 26.6% below 26th of 58
Gonorrhea 125.3910 cases 190.2 178.2 34.1% below 29.7% below 17th of 58
Syphilis (P&S) 9.267 cases 16.3 15.8 43.6% below 41.8% below 41st of 58

Rates per 100,000 residents, 2023. Ranks run from the highest rate (1st) among California’s counties. The US rate is all 50 states combined. Comparisons are left out where fewer than 20 cases were reported, because a rate built on so few cases can swing widely from one year to the next.

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FAQs

San Mateo County ranks 25th of 58 California counties for combined STD rate in 2023, at 494.9 per 100,000 residents.
In 2023, chlamydia was the most frequently reported STD in San Mateo County, with 2,618 cases at a rate of 360.4 per 100,000 residents.
STDTest.com lists confidential testing locations across San Mateo County and California. Many offer same-day appointments with results in 1–3 days.
Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.