STD Rates in California

CDC surveillance data for California covering chlamydia, gonorrhea, syphilis, and HIV — with 15-year trends, state rankings, and national comparisons.

Data Year: 2023 Source: CDC STI Surveillance Population: 38,965,193
US map with California highlighted, showing a combined STD rate of 697.6 per 100,000
697.6per 100K combined
#20 / 50 states
Combined
697.6
per 100K
20th / 50
Chlamydia
491.1
per 100K • 191,357 cases
-0.5 from 2022
US median: 471.3
Gonorrhea
190.2
per 100K • 74,103 cases
-7.5 from 2022
US median: 152.2
Syphilis P&S
16.3
per 100K • 6,348 cases
-18.9 from 2022
US median: 14.8

California ranks 20th out of 50 states for combined STD burden — squarely in the upper half, with a combined rate of 697.6 per 100,000 people. That ranking alone isn't the story, though. What's more telling is the direction things are moving: after years of climbing, California's rates for all three major STDs dropped in 2023. Gonorrhea and syphilis fell the most. Whether that's a turning point or a single-year fluctuation is the open question.

Chlamydia is California's highest-volume disease by far — 191,357 cases in 2023, at a rate of 491.1 per 100,000. That puts the state just above the national median of 471.3, but only barely. The more notable fact is what happened over time: chlamydia rates rose steadily from 280 per 100,000 in 2000, peaked near 600 in 2019, then fell sharply in 2020 — almost certainly a testing artifact from the pandemic — and have been plateauing since. The 0.5% dip in 2023 keeps the trend flat rather than reversing it.

Gonorrhea tells a sharper story. Since 2008, California's gonorrhea rate has risen 169% — from 70.6 to 190.2 per 100,000. That puts the state 25% above the national median of 152.2. The rate peaked at 233.1 in 2021 and has been pulling back since, with a 7.5% drop in 2023. Syphilis followed a similar arc: it climbed from 6 per 100,000 in 2008 to a high of 22.2 in 2021, then fell to 16.3 by 2023 — an 18.9% single-year decline, and now just above the national median of 14.8. Two diseases rising sharply, then retreating in tandem — that's not a coincidence, and it's worth watching.

HIV data runs through 2022. California recorded 4,899 new diagnoses that year, at a rate of 14.8 per 100,000 — nearly back to 2017 levels after a brief drop during the pandemic years. New diagnoses fell to a low of 4,138 in 2020, but that dip almost certainly reflects disrupted testing rather than reduced transmission. If you're in Los Angeles, San Francisco, or San Diego — cities that have historically driven California's HIV and STD numbers — STDTest.com can help you find a testing location nearby.

STD Trends in California

Chlamydia
491.1
per 100,000 • 191,357 cases
-0.5 from 2022
20.6 since 2008

California's chlamydia rate has been essentially flat for three years, hovering just above the national median of 471.3. The plateau follows a long climb — rates nearly doubled between 2000 and 2019 — but the 2023 figure of 491.1 represents a 0.5% decline, the second consecutive year without meaningful growth. The long-run rise of roughly 20% since 2008 is modest compared to gonorrhea and syphilis, suggesting chlamydia trends in California have stabilized even as other diseases continued climbing.

Gonorrhea
190.2
per 100,000 • 74,103 cases
-7.5 from 2022
169.4 since 2008

Gonorrhea has been California's fastest-moving STD over the past 15 years. The rate rose 169% from 2008 to its 2021 peak, and even after two years of decline, it sits at 190.2 per 100,000 — 25% above the US median of 152.2. The 7.5% drop in 2023 is real, but it follows a period of such sustained growth that California remains well above where it was a decade ago.

Syphilis (P&S)
16.3
per 100,000 • 6,348 cases
-18.9 from 2022
171.7 since 2008

Syphilis in California surged from 6 per 100,000 in 2008 to 22.2 in 2021 — nearly four times the starting rate in 13 years. The recent reversal has been sharper than the other diseases: an 18.9% drop in 2023 brought the rate to 16.3, just above the national median of 14.8. That's a notable shift, but the rate is still nearly three times what it was in 2008.

HIV
14.8
per 100,000 • 4,899 cases

California's HIV data covers 2017 through 2022. New diagnoses fell from 4,920 in 2017 to a low of 4,138 in 2020, but that drop lines up with pandemic-era testing disruptions rather than a genuine reduction in transmission — the number climbed back to 4,899 by 2022. The overall trend since 2017 is essentially flat, with the state recording a rate of 14.8 per 100,000 in 2022, nearly identical to where it started.

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California vs National Average

Comparing 2023 rates against the U.S. median across all 50 states.

InfectionCaliforniaUS MedianDifference
Chlamydia491.1471.34.2% above
Gonorrhea190.2152.225% above
Syphilis (P&S)16.314.810.1% above

What the numbers mean — and what to do about them

Nearly 272,000 Californians were diagnosed with chlamydia, gonorrhea, or syphilis in 2023. That's a combined rate of 697.6 per 100,000 — ninth-largest state population in terms of raw numbers, and a disease burden that puts California in the upper half nationally. The good news, if you want to call it that, is that all three rates fell in 2023. The less comfortable truth is that gonorrhea is still 25% above the national median, and syphilis — despite its sharp recent decline — is nearly three times its 2008 rate.

The trend that matters most clinically is gonorrhea's long rise. A 169% increase since 2008 doesn't happen because people are getting more symptomatic infections — it happens because gonorrhea frequently produces no symptoms at all, especially in women, and infections go undetected without testing. The same applies to chlamydia, which accounts for the majority of California's STD case volume. When rates climb that steadily over that long a period, the gap between diagnosed cases and actual infections tends to grow quietly alongside them.

If you live in California — especially in Los Angeles, San Francisco, or San Diego, where STD and HIV case counts are concentrated — regular testing is one of the few ways to know where you actually stand. California's gonorrhea rate spent more than a decade climbing while most people had no idea. STDTest.com can show you where to get tested today, so you're not one of the cases that goes undetected.

WHO SHOULD GET TESTED

Sexually active adults in California — particularly those in Los Angeles, San Francisco, and San Diego, where STD rates are highest. California's gonorrhea rate is 25% above the national median, and chlamydia remains above average, making routine screening relevant even for people without symptoms. Gay and bisexual men face elevated risk for both gonorrhea and syphilis given California's historical case distribution.

HOW OFTEN

At least once a year if you're sexually active. Given that California's gonorrhea and syphilis rates — even after recent declines — remain above national medians, twice-yearly testing makes sense if you have multiple partners. The post-2021 declines in syphilis and gonorrhea are real, but rates are still well above where they were a decade ago.

WHAT TO EXPECT

Testing is straightforward — typically a urine sample and a blood draw, sometimes a swab depending on the test. Most results come back within a few days. Many clinics in California offer same-day appointments and confidential results. If a test comes back positive, treatment for chlamydia, gonorrhea, and syphilis is available and effective.

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FAQs

California's syphilis rate fell from 20.1 to 16.3 per 100,000 between 2022 and 2023 — an 18.9% single-year decline. That follows a peak of 22.2 in 2021, suggesting the post-pandemic surge may be receding. The rate remains above the national median of 14.8 and nearly three times the 2008 baseline, so the trend bears watching.
California ranks 20th out of 50 states for combined STD burden, with a combined rate of 697.6 per 100,000 — about 9% above the US combined median. Its gonorrhea rate of 190.2 is 25% above the national median of 152.2, while chlamydia at 491.1 sits just above the median of 471.3.
Close — it rose 169% from 70.6 per 100,000 in 2008 to a peak of 233.1 in 2021. The 2023 rate of 190.2 reflects two years of decline, but the state remains significantly above its historical baseline and above the current national median of 152.2.
STDTest.com lists testing locations across California, including clinics in Los Angeles, San Francisco, and San Diego. These cities have historically accounted for a substantial share of California's STD and HIV case counts, and same-day or next-day appointments are often available at listed locations.
With California's gonorrhea rate 25% above the national median and chlamydia still above the national average, annual testing is a reasonable baseline for sexually active adults — more frequently if you have multiple partners or live in a higher-burden metro area like Los Angeles or San Francisco. Both chlamydia and gonorrhea are often asymptomatic, meaning people can carry and transmit infections without knowing it.
Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.