STD Testing in Yankton, SD

3 places to get tested — 3 clinics and testing sites near Yankton, and no partner lab. The nearest one is out of town, so an at-home kit is usually the quicker route.

  • 1free clinic
  • 2sliding scale

Order a test online

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Buy an at-home STD test near Yankton and online

Walgreens and Walmart sell over-the-counter test kits near Yankton, and myLAB Box ships one to your door. You collect the sample at home and mail it to a lab. Stock varies by branch — call ahead or check online before making the trip.

We earn a commission if you order a myLAB Box kit through the link above. It does not change what you pay, and it does not decide which pharmacies are listed — those are the chains with branches near Yankton.

Clinics and testing sites near Yankton

No free or low-cost clinic is addressed in Yankton itself, so the nearest are listed below, closest first. Public clinics generally take longer to return results than a private lab, and several test on set days only, so it is worth calling ahead. If you would rather not wait or give your details at a public clinic, an at-home collection kit posts back to a lab and needs no local appointment at all.

How we chose these 3 clinics

  • Every one is on the CDC’s GetTested locatorThe wider CDC directory we draw from has over 16,000 entries. Only the ones GetTested also lists can appear here, and all 3 clinics below do.
  • Listings that name fewer than three tests are left outEven on GetTested, 527 listings name fewer than three tests. We don’t show them anywhere.
  • Unverified pregnancy centers are never shownThe CDC lists some pregnancy centers whose STD testing we couldn’t verify. We don’t list them anywhere.
  • Cost is stated the way the CDC lists itFree, sliding scale or insurance accepted, as each clinic reports it to the CDC. We don’t estimate prices, and if the listing says nothing, the card says “Fees not listed.”

Directory retrieved September 4, 2026. Open “View services” on any card to see when that clinic last updated its listing. All sources

  • Community health center0.8 mi away

    Horizon Health Care

    Yankton Community Health Center

    920 Broadway Ave, Yankton, SD, 57078

    Hours
    Mon-Thu 7:00am-5:30pm+1Fri 7:00am-4:30pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • Treats STIs
    • Medicaid accepted
    • Interpretation listed
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C · Hepatitis A · TB

    Treatments STI treatment · Family planning · HPV vaccine · Hep B vaccine · Case management

    Languages English · interpreter available

    CDC GetTested listing, last updated by the source February 3, 2026. Directory retrieved September 4, 2026.

  • Public health department47.7 mi away

    Indian Health Service

    Wagner Health Care Facility

    111 Washington Ave NW, Wagner, SD, 57380

    Hours
    Mon-Sun 7:00am-11:00pm
    AppointmentsWalk-ins accepted
    FeesFree STI testing listed
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C · Hepatitis A · TB

    Treatments STI treatment · PrEP · PEP · HIV care · Hep C treatment · Family planning · HPV vaccine · Hep B vaccine · Free condoms · Case management

    Languages English

    CDC GetTested listing, last updated by the source April 13, 2026. Directory retrieved September 4, 2026.

  • Community organization35.3 mi away

    Faith Health

    Laurel Family Medicine

    218 E 2nd St, Laurel, NE, 68745

    Hours
    Mon-Thu 8:00am-5:00pm+1Fri 8:00am-12:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C · Hepatitis A · TB

    Treatments STI treatment · Family planning · HPV vaccine · Hep B vaccine

    Languages English

    CDC GetTested listing, last updated by the source March 25, 2026. Directory retrieved September 4, 2026.

Explore testing locations in and near Yankton

Partner lab · 1Clinic · 3every partner lab in Yankton, plus the clinics listed on this page, within 48 miles

Nearest partner lab

No partner lab operates in Yankton. The closest one is listed below — for most readers here an at-home kit is the quicker option, but the lab is there if you would rather give a sample in person.

  • Sanford Laboratories

    34 mi awayIn Beresford, not Yankton

    600 W Cedar St, Beresford, SD 57004 · Mon-Fri 8:00 am to 5:00 pm

Yankton County STD rates

Reported cases per 100,000 residents. Change shown against the year before.

Chlamydia

▼ 16.4%

293.4per 100k

69 reported cases · 2023 · 45% below the SD rate

Gonorrhea

▼ 39.5%

59.5per 100k

14 reported cases · 2023 · 77% below the SD rate

Syphilis

▼ 83.3%

4.3per 100k

1 reported cases · 2023 · 94% below the SD rate

HIV

5new diagnoses

2023 · rate not published

Source: CDC NCHHSTP AtlasPlus, 2023 release · Yankton County SD STD Statistics

There were 5 new HIV diagnoses in Yankton County in 2023. HIV is the one infection where how soon you test changes which test you need — an RNA test detects it far earlier than a standard antibody test.

Yankton County reported 69 chlamydia cases in 2023, a rate of 293.4 per 100,000 residents. Most people who have chlamydia or gonorrhea have no symptoms at all, so waiting for something to feel wrong is not a strategy.

HIV prevention & treatment

PrEP, DoxyPEP & Online Treatment

A test result is the start, not the end. If you are negative and want to stay that way, PrEP and DoxyPEP cut the risk of a future infection. If you are positive, most STIs can be treated without setting foot in a clinic. Both are available to people in Yankton by video visit, prescribed by clinicians licensed in South Dakota.

  • Treatment & DoxyPEP

    Wisp

    STI treatment $39 · DoxyPEP from $22

    Treatment for an STI, and DoxyPEP, prescribed online. The prescription goes to your pharmacy the same day.

    Visit Wisp
  • HIV PrEP & DoxyPEP

    Q Care Plus

    $0 for most insured patients

    PrEP and DoxyPEP by video visit, with test kits posted to you and follow-up bloodwork tracked between refills.

    Visit Q Care Plus
  • HIV PrEP & DoxyPEP

    MISTR

    $0 with or without insurance

    HIV prevention handled entirely from home: PrEP and the lab work that goes with it, no appointment.

    Visit MISTR

Prices depend on your insurance and change frequently — check the provider’s own site before ordering. None of these replace emergency care.

STD testing in Yankton, answered

Where can I find free or sliding-scale STD testing near Yankton?

Among the 3 clinics listed near Yankton, 1 lists free testing for at least one infection and 2 list sliding-scale fees. Confirm eligibility and charges before visiting. Free testing is listed at Indian Health Service.

How much does STD testing cost near Yankton?

Among the 3 clinics listed near Yankton, 1 list free testing for at least one infection and 2 charge on a sliding scale based on income. Private lab testing is a flat price paid up front — no insurance is filed, so nothing appears on an explanation of benefits.

Can I get tested on a weekend near Yankton?

1 of the 3 listed clinics publish Saturday hours: Indian Health Service. The partner labs are weekday only, so a Saturday visit means one of the community clinics.

How common are STDs in Yankton?

In 2023, Yankton County reported 69 chlamydia cases — a rate of 293.4 per 100,000 residents. Gonorrhea was 59.5 per 100,000. There were also 5 new HIV diagnoses in 2023.

Data and sources
Partner labs
Quest and Labcorp location directories · checked August 2026
Public clinics
CDC GetTested / NPIN directory · retrieved September 4, 2026
Retailers
Retailer store directories · updated September 2026
Statistics
CDC NCHHSTP AtlasPlus · reporting year 2023
HIV diagnoses
CDC HIV Surveillance · reporting year 2023
Services, eligibility and hours can change. Contact the location before visiting. This page is informational and is not medical advice.

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