STD Testing in Holyoke, MA

14 places to get tested — 4 partner labs that need no appointment, and 10 clinics and testing sites near Holyoke.

  • 4partner labs
  • 2free clinics
  • 7sliding scale
  • 1insurance or fee

Order a test online

Pick a panel, visit a lab nearby, results in 1–2 days. No appointment, no insurance.

GET TESTED NOWCompare pricing →4,500+ labs nationwide · from $24

Partner labs near Holyoke

Order online, then walk in the same day with no appointment. A urine or blood sample takes about 15 minutes, and results come back in 1–2 days. They are confidential: never reported to your insurance company or added to your medical record.

  • Quest Diagnostics

    4.8 mi awayNo appointment

    1284 Saint James Ave, Springfield, MA 01104 · Mon-Fri 8:00 am to 4:30 pm · nearby in Springfield

    $10 off orders over $100 applied at checkoutOrder a test for this lab →
  • Quest Diagnostics

    9.1 mi awayNo appointment

    6 Hatfield St, Northampton, MA 01060 · Mon-Fri 7:00 am to 3:30 pm · nearby in Northampton

    $10 off orders over $100 applied at checkoutOrder a test for this lab →
  • Quest Diagnostics

    15.0 mi awayNo appointmentOpen Saturday

    54 Hazard Ave, Suite 90, Enfield, CT 06082 · Mon-Fri 6:00 am to 4:00 pm · nearby in Enfield

    $10 off orders over $100 applied at checkoutOrder a test for this lab →
  • Labcorp

    15.3 mi awayNo appointmentOpen Saturday

    160 Hazard Avenue, Enfield, CT 06082 · Mon-Fri 7:30 am to 5:00 pm · nearby in Enfield

    $10 off orders over $100 applied at checkoutOrder a test for this lab →

We earn a commission if you order through the links above. It does not change what you pay, and it does not decide which labs are listed — those are the closest partner labs to Holyoke.

Explore testing locations in and near Holyoke

Partner lab · 7Clinic · 10every partner lab in Holyoke, plus the clinics listed on this page, within 15 miles

Clinics and testing sites near Holyoke

No free or low-cost clinic is addressed in Holyoke itself, so the nearest are listed below, closest first. Public clinics generally take longer to return results than a private lab, and several test on set days only, so it is worth calling ahead. If you would rather not wait or give your details at a public clinic, the 4 partner labs in Holyoke need no appointment and return results in 1–2 days.

How we chose these 10 clinics

  • Every one is on the CDC’s GetTested locatorThe wider CDC directory we draw from has over 16,000 entries. Only the ones GetTested also lists can appear here, and all 10 clinics below do.
  • Listings that name fewer than three tests are left outEven on GetTested, 527 listings name fewer than three tests. We don’t show them anywhere.
  • Unverified pregnancy centers are never shownThe CDC lists some pregnancy centers whose STD testing we couldn’t verify. We don’t list them anywhere.
  • Cost is stated the way the CDC lists itFree, sliding scale or insurance accepted, as each clinic reports it to the CDC. We don’t estimate prices, and if the listing says nothing, the card says “Fees not listed.”

Directory retrieved September 4, 2026. Open “View services” on any card to see when that clinic last updated its listing. All sources

  • Community health center0.5 mi away

    Holyoke Health

    Holyoke Health Center

    230 Maple St, Holyoke, MA, 01040

    Hours
    Mon-Wed 8:30am-8:00pm+2Thu-Fri 8:30am-4:30pm · Sat 9:00am-1:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Hepatitis B · Hepatitis C · Hepatitis A · TB

    Treatments STI treatment · PrEP · PEP · HIV care · Hep C treatment · Family planning · Ryan White · HPV vaccine · Hep B vaccine · Free condoms · PrEP navigation · Case management

    Languages English · Spanish

    CDC GetTested listing, last updated by the source June 24, 2026. Directory retrieved September 4, 2026.

  • Clinic0.5 mi away

    Tapestry

    Holyoke Office

    306 Race St, Holyoke, MA, 01040

    Hours
    Mon 10:00am-6:00pm+2Wed 9:00am-5:00pm · Fri 9:00am-5:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis C

    Treatments STI treatment · PrEP · PEP · Family planning · HPV vaccine · Mpox vaccine · Harm reduction

    Languages English · Spanish

    CDC GetTested listing, last updated by the source March 25, 2026. Directory retrieved September 4, 2026.

  • Clinic5.4 mi away

    Planned Parenthood League of Massachusetts

    Western Massachusetts Health Center

    3550 Main St, Springfield, MA, 01107

    Hours
    Mon 7:40am-4:00pm+4Tue 7:40am-8:00pm · Wed 7:40am-4:00pm · Thu 7:40am-8:00pm · Fri 7:40am-4:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C

    Treatments STI treatment · PrEP · PEP · Family planning · HPV vaccine · Free condoms · PrEP navigation

    Languages English · Spanish · interpreter available

    CDC GetTested listing, last updated by the source June 18, 2026. Directory retrieved September 4, 2026.

  • Clinic5.6 mi away

    Baystate Health

    Tolosky Center

    3300 Main St, Springfield, MA, 01107

    Hours
    Mon-Fri 8:00am-5:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • Treats STIs
    • Medicaid accepted
    • Spanish spoken
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · TB

    Treatments STI treatment · HIV care · Hep C treatment · HPV vaccine · Hep B vaccine · Case management

    Languages English · Spanish

    CDC GetTested listing, last updated by the source February 11, 2026. Directory retrieved September 4, 2026.

  • Community organization6.9 mi away

    New North Citizens Council Incorporated

    NNCC Drop In Center

    34-38 Catherine St, Springfield, MA, 01109

    Hours
    Mon-Fri 8:30am-5:00pm
    AppointmentsAppointment required
    FeesFree STI testing listed
    • HIV & STI testing
    • Spanish spoken
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Hepatitis C

    Treatments Case management

    Languages English · Spanish

    CDC GetTested listing, last updated by the source April 7, 2026. Directory retrieved September 4, 2026.

  • Community health center7.3 mi away

    Caring Health Center

    1235 Boston Rd, Springfield, MA, 01119

    Hours
    Mon-Fri 8:30am-5:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • PrEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C · TB

    Treatments STI treatment · PrEP · HIV care · Hep C treatment · Family planning · Ryan White · HPV vaccine · Hep B vaccine · Free condoms · PrEP navigation · Case management

    Languages English

    CDC GetTested listing, last updated by the source April 3, 2026. Directory retrieved September 4, 2026.

  • Clinic7.3 mi away

    Infectious Disease and The Research Institute

    57 Mulberry St, Springfield, MA, 01105

    Hours
    Mon-Fri 9:00am-4:00pm
    AppointmentsAppointment required
    FeesInsurance accepted
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Spanish spoken
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Herpes · Hepatitis B · Hepatitis C · TB

    Treatments STI treatment · PrEP · PEP · HIV care · Hep C treatment · HPV vaccine · Hep B vaccine · Case management

    Languages English · Spanish

    CDC GetTested listing, last updated by the source February 4, 2026. Directory retrieved September 4, 2026.

  • Community organization7.8 mi away

    Cooley Dickinson Health Care

    2 Conz St, Northampton, MA, 01060

    Hours
    Mon-Fri 9:00am-5:00pm
    AppointmentsWalk-ins accepted
    FeesFree STI testing listed
    • HIV & STI testing
    • PrEP & PEP
    • Treats STIs
    • Spanish spoken
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Hepatitis C

    Treatments STI treatment · PrEP · PEP · HIV care · Hep C treatment · Ryan White · Free condoms · Harm reduction · PrEP navigation · Case management

    Languages English · Spanish · interpreter available

    CDC GetTested listing, last updated by the source February 20, 2026. Directory retrieved September 4, 2026.

  • Community health center12.9 mi away

    Hilltown Community Health Center

    John P Musante Health Center

    70 Boltwood Walk, Pelham, MA, 01002

    Hours
    Mon-Fri 8:00am-5:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • Treats STIs
    • Medicaid accepted
    • Interpretation listed
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · TB

    Treatments STI treatment · Family planning · HPV vaccine · Hep B vaccine

    Languages English · interpreter available

    CDC GetTested listing, last updated by the source July 20, 2026. Directory retrieved September 4, 2026.

  • Community health center14.2 mi away

    Community Health Center Incorporated

    Mary Lou Strom Primary Care Center

    5 N Main St, Enfield, CT, 06082

    Hours
    Mon-Fri 8:00am-5:00pm
    AppointmentsAppointment required
    FeesSliding scale listed
    • HIV & STI testing
    • PrEP
    • Treats STIs
    • Medicaid accepted
    CallWebsiteDirections
    View services

    Tests Chlamydia · Gonorrhea · Syphilis · HIV · Hepatitis C

    Treatments STI treatment · PrEP · Family planning · HPV vaccine · Hep B vaccine · Mpox vaccine · PrEP navigation

    Languages English · Spanish

    CDC GetTested listing, last updated by the source November 26, 2025. Directory retrieved September 4, 2026.

Testing privacy

Anonymous vs. confidential testing

Most clinics test confidentially. Some also offer anonymous testing, usually for HIV. Availability varies by testing site, so ask when you call.

Confidential

  • You give your name, and the result goes in your medical record.
  • Results are not available to the public.
  • Chlamydia, gonorrhea, syphilis and HIV are reportable in every state, so a positive result is reported to the health department. Those reports are kept confidential.

Anonymous

  • You don’t give your name.
  • You receive a number and use it, not your name, to get your result.
  • Not every site offers it. Ask before your visit.

Source: NIH HIVinfo, HIV Testing · CDC, STI Reporting and Confidentiality

Buy an at-home STD test near Holyoke and online

CVS Pharmacy, Walgreens, Target and Walmart sell over-the-counter test kits near Holyoke, and myLAB Box ships one to your door. You collect the sample at home and mail it to a lab. Stock varies by branch — call ahead or check online before making the trip.

We earn a commission if you order a myLAB Box kit through the link above. It does not change what you pay, and it does not decide which pharmacies are listed — those are the chains with branches near Holyoke.

Hampden County STD rates

Reported cases per 100,000 residents. Change shown against the year before.

Chlamydia

▲ 2.5%

572.5per 100k

2,635 reported cases · 2023 · 39% above the MA rate

Gonorrhea

▼ 18.6%

177.5per 100k

817 reported cases · 2023 · 27% above the MA rate

Syphilis

▲ 20.2%

23.2per 100k

107 reported cases · 2023 · 119% above the MA rate

HIV

▲ 34.4%

43new diagnoses

2023 · rate not published

Source: CDC NCHHSTP AtlasPlus, 2023 release · Hampden County MA STD Statistics

There were 43 new HIV diagnoses in Hampden County in 2023. HIV is the one infection where how soon you test changes which test you need — an RNA test detects it far earlier than a standard antibody test.

Hampden County reported 2,635 chlamydia cases in 2023, a rate of 572.5 per 100,000 residents. That is above the national average, which is why routine testing matters here more than it does in most of the country — and most people who have chlamydia or gonorrhea have no symptoms at all, so waiting for something to feel wrong is not a strategy.

HIV prevention & treatment

PrEP, DoxyPEP & Online Treatment

A test result is the start, not the end. If you are negative and want to stay that way, PrEP and DoxyPEP cut the risk of a future infection. If you are positive, most STIs can be treated without setting foot in a clinic. Both are available to people in Holyoke by video visit, prescribed by clinicians licensed in Massachusetts.

  • Treatment & DoxyPEP

    Wisp

    STI treatment $39 · DoxyPEP from $22

    Treatment for an STI, and DoxyPEP, prescribed online. The prescription goes to your pharmacy the same day.

    Visit Wisp
  • HIV PrEP & DoxyPEP

    Q Care Plus

    $0 for most insured patients

    PrEP and DoxyPEP by video visit, with test kits posted to you and follow-up bloodwork tracked between refills.

    Visit Q Care Plus
  • HIV PrEP & DoxyPEP

    MISTR

    $0 with or without insurance

    HIV prevention handled entirely from home: PrEP and the lab work that goes with it, no appointment.

    Visit MISTR

Prices depend on your insurance and change frequently — check the provider’s own site before ordering. None of these replace emergency care.

STD testing in Holyoke, answered

Where can I find free or sliding-scale STD testing near Holyoke?

Among the 10 clinics listed near Holyoke, 2 list free testing for at least one infection and 7 list sliding-scale fees. Confirm eligibility and charges before visiting. Free testing is listed at New North Citizens Council Incorporated, Cooley Dickinson Health Care.

How much does STD testing cost near Holyoke?

Among the 10 clinics listed near Holyoke, 2 list free testing for at least one infection and 7 charge on a sliding scale based on income. Private lab testing is a flat price paid up front — no insurance is filed, so nothing appears on an explanation of benefits.

Can I get tested on a weekend near Holyoke?

1 of the 10 listed clinics publish Saturday hours: Holyoke Health. Some partner labs also open on Saturday — the cards above show which.

How common are STDs in Holyoke?

In 2023, Hampden County reported 2,635 chlamydia cases — a rate of 572.5 per 100,000 residents. Gonorrhea was 177.5 per 100,000. There were also 43 new HIV diagnoses in 2023.

Is testing available in Spanish near Holyoke?

8 of the 10 listed clinics indicate that Spanish-language services are available, and 7 list PrEP.

Data and sources
Partner labs
Quest and Labcorp location directories · checked August 2026
Public clinics
CDC GetTested / NPIN directory · retrieved September 4, 2026
Retailers
Retailer store directories · updated September 2026
Statistics
CDC NCHHSTP AtlasPlus · reporting year 2023
HIV diagnoses
CDC HIV Surveillance · reporting year 2023