STD Rates in Greenville County, South Carolina

2023 CDC surveillance data for Greenville County, South Carolina — chlamydia, gonorrhea, and syphilis rates with state comparisons.

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Data Year: 2023 Source: CDC STI Surveillance Population: 558,078
Combined
729.6
per 100K
30th / 46
Chlamydia
528.6
per 100K • 2,950 cases
Gonorrhea
185.8
per 100K • 1,037 cases
Syphilis P&S
15.2
per 100K • 85 cases

Greenville County recorded a combined STD rate of 729.6 per 100,000 residents in 2023, ranking 30th of 46 counties in South Carolina. Reported infections included chlamydia at 528.6 per 100,000 (2,950 cases, 14% below the state rate), gonorrhea at 185.8 per 100,000 (1,037 cases, 16% below the state rate), syphilis at 15.2 per 100,000 (85 cases, 12% below the state rate). Confidential STD testing is available throughout Greenville County — knowing your status is the only way to catch infections that often show no symptoms.

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Greenville County vs South Carolina Average

Infection Greenville County South Carolina Rate Difference
Chlamydia 528.6 612.1 14% below
Gonorrhea 185.8 222.4 16% below
Syphilis (P&S) 15.2 17.3 12% below

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Largest cities in Greenville County, South Carolina

Largest first, by Census population. Each city page lists nearby clinics, free and low-cost testing, and labs.

STD testing in Greenville, SC72,935 people → STD testing in Greer, SC41,536 people → STD testing in Mauldin, SC27,055 people → STD testing in Simpsonville, SC26,144 people → STD testing in Taylors, SC24,505 people → STD testing in Wade Hampton, SC20,898 people → STD testing in Five Forks, SC18,656 people → STD testing in Berea, SC16,862 people → STD testing in Gantt, SC15,401 people → STD testing in Parker, SC12,898 people →
Show all 12 cities ↓Show fewer cities ↑
STD testing in Highland, SC → STD testing in Woodville, SC →

Largest Counties in South Carolina

Richland County → Charleston County → Horry County → Spartanburg County → Lexington County → York County → Berkeley County → Anderson County → Beaufort County → Aiken County →

All 46 South Carolina counties → STD testing in South Carolina →

FAQs

Greenville County ranks 30th of 46 South Carolina counties for combined STD rate in 2023, at 729.6 per 100,000 residents.
In 2023, chlamydia was the most frequently reported STD in Greenville County, with 2,950 cases at a rate of 528.6 per 100,000 residents.
STDTest.com lists confidential testing locations across Greenville County and South Carolina. Many offer same-day appointments with results in 1–3 days.

Related Resources

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Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.
Sources