STD Rates in Wyoming
CDC surveillance data for Wyoming covering chlamydia, gonorrhea, syphilis, and HIV — with 15-year trends, state comparisons, and 2023 case rates.
Wyoming has one of the lowest STD burdens in the country. Its combined rate of 357.7 per 100,000 residents ranks 45th out of 50 states — well below the national median. But low-ranking states aren't uniform, and Wyoming's individual disease trends don't all point in the same direction.
Chlamydia is the quietest part of Wyoming's story. The state recorded 1,829 cases in 2023, a rate of 313.2 per 100,000 — about a third below the national median of 471.3. The rate has barely moved in a decade, rising just 5.8% since 2008 and ticking up only 1.6% from 2022 to 2023. That kind of plateau is unusual; most states saw sharper climbs over the same period.
Gonorrhea tells a different story. Wyoming's rate of 42.3 per 100,000 is still well below the national median of 152.2, but it has climbed 81.5% since 2008 — starting from nearly nothing. In 2010, the gonorrhea rate was 7.1. By 2021, it had hit 90.4. The two years since have brought some relief: the rate fell 20.6% from 2022 to 2023, part of a pullback from that 2021 peak. Syphilis followed a similar arc — it spiked to 4.0 per 100,000 in 2018 and has been declining since, dropping 38.9% in 2023 alone to 2.2, still well below the national median of 14.8.
Wyoming's HIV numbers are modest but not static. New diagnoses averaged around 12 cases per year from 2017 to 2022, with a dip to 7 cases in 2021 that likely reflects pandemic-era disruptions to testing access rather than a true decline — cases bounced back to 14 in 2022. If you live in Cheyenne, Casper, or Laramie and haven't been tested recently, STDTest.com can help you find a location nearby.
STD Trends in Wyoming
Wyoming's chlamydia rate has essentially flatlined for over a decade — which makes it an outlier. At 313.2 per 100,000, it sits roughly 34% below the national median of 471.3, and the long-run increase since 2008 is just 5.8%. Whether that reflects genuinely lower transmission or lower testing rates in a rural state is a real question worth sitting with.
Gonorrhea has been Wyoming's fastest-moving STD over the past 15 years, rising 81.5% since 2008 from a very low base. The rate peaked at 90.4 per 100,000 in 2021 before pulling back to 42.3 in 2023 — still more than four times the 2010 low of 7.1. Even with the recent decline, the long-run trajectory shows a disease that gained real ground in a state where it was once barely detectable.
Syphilis in Wyoming peaked at 4.0 per 100,000 in 2018, then became volatile — dropping, rising, and dropping again. The 2023 rate of 2.2 reflects a 38.9% fall from 2022 and sits well below the national median of 14.8. Wyoming has never sustained a syphilis epidemic in the way other states have, but the years between 2016 and 2022 showed it isn't immune to the national surge pattern either.
Wyoming's HIV data runs through 2022 and shows a state with consistently low new diagnosis counts — typically 10 to 14 cases per year. The 2021 figure of 7 cases stands out, but it almost certainly reflects reduced testing access during the pandemic rather than an actual transmission drop, given that cases returned to 14 in 2022. At a rate of 2.8 per 100,000, Wyoming remains among the lowest in the country for new HIV diagnoses.
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Wyoming vs National Average
Comparing 2023 rates against the U.S. median across all 50 states.
| Infection | Wyoming | US Median | Difference |
|---|---|---|---|
| Chlamydia | 313.2 | 471.3 | 33.5% below |
| Gonorrhea | 42.3 | 152.2 | 72.2% below |
| Syphilis (P&S) | 2.2 | 14.8 | 85.1% below |
What the numbers mean — and what to do about them
Wyoming's STD numbers are among the lowest in the country — but low isn't the same as zero. In 2023, nearly 2,100 Wyoming residents were diagnosed with chlamydia, gonorrhea, or syphilis combined. For a state of roughly 584,000 people, that works out to about 1 in every 275 residents receiving a new diagnosis in a single year. Most of those cases were in people who had no idea they were infected.
The trend that matters most in Wyoming's data is gonorrhea's long climb. A disease that was nearly absent in 2010 — with a rate of just 7.1 per 100,000 — reached 90.4 in 2021 before pulling back. Even at today's lower rate of 42.3, gonorrhea is far more common in Wyoming than it was a decade ago, and like chlamydia, it frequently causes no symptoms. That means transmission continues quietly, and cases go uncounted until someone gets tested. Wyoming's gonorrhea rate climbed for over a decade without most people in the state noticing. If you haven't been tested recently, that's the number to keep in mind.
If you're in Cheyenne, Casper, or Laramie — Wyoming's three largest cities and the places where most of the state's diagnoses are concentrated — getting tested is straightforward. Most clinics offer same-week appointments, and results typically come back within a few days. Wyoming's gonorrhea rate has nearly quadrupled since 2010, and chlamydia still accounts for more than 1,800 annual diagnoses in a small state. STDTest.com can show you exactly where to get tested today.
WHO SHOULD GET TESTED
Sexually active adults in Wyoming — particularly those under 25, who account for the largest share of chlamydia cases nationally, and anyone with new or multiple partners. Wyoming's gonorrhea rate is well below the national median but has risen sharply over 15 years, making testing relevant even in a low-prevalence state. If you live in or near Cheyenne, Casper, or Laramie, access to testing is easy — there's no reason to skip it.
HOW OFTEN
Once a year is a reasonable floor for sexually active adults given Wyoming's overall low but non-trivial STD rates. If you have multiple partners or a new partner, every three to six months makes sense — especially for gonorrhea, which climbed steadily in Wyoming for over a decade and still sits well above its 2010 baseline. Annual testing for chlamydia is particularly important since Wyoming's 1,829 cases in 2023 skew heavily asymptomatic.
WHAT TO EXPECT
A standard STD panel usually involves a urine sample, a blood draw, or a swab — sometimes a combination depending on what you're being tested for. It takes 10 to 15 minutes. Results typically come back within two to five days, and most clinics handle everything confidentially. If something comes back positive, treatment for chlamydia, gonorrhea, and syphilis is straightforward with antibiotics.
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