STD Rates in Alabama

CDC surveillance data for Alabama covering chlamydia, gonorrhea, syphilis, and HIV — with 15-year trends and national comparisons.

Data Year: 2023 Source: CDC STI Surveillance Population: 5,108,468
US map with Alabama highlighted, showing a combined STD rate of 906.6 per 100,000
906.6per 100K combined
#5 / 50 states
Combined
906.6
per 100K
5th / 50
Chlamydia
651.1
per 100K • 33,261 cases
6.4 from 2022
US median: 471.3
Gonorrhea
226.9
per 100K • 11,592 cases
-13.3 from 2022
US median: 152.2
Syphilis P&S
28.6
per 100K • 1,460 cases
21.7 from 2022
US median: 14.8

Alabama has one of the highest STD burdens in the country. The state's combined rate of 906.6 cases per 100,000 people ranks 5th nationally — meaning only four states report more STDs per capita. That ranking alone would be noteworthy. What makes it more complicated is that the trajectory on syphilis, in particular, keeps moving in the wrong direction even as gonorrhea has started to pull back.

Chlamydia is the state's highest-volume disease, with more than 33,000 diagnoses in 2023 at a rate of 651.1 per 100,000. That's 38% above the national median of 471.3. The long-run picture is telling: since 2008, Alabama's chlamydia rate has climbed nearly 23%, and 2023 marked a new recent high. There's no plateau here — the rate ticked up another 6.4% from 2022 to 2023 alone.

Gonorrhea is the one disease where Alabama's numbers actually moved in a favorable direction this past year — down 13.3% from 2022 to 2023. But context matters. The rate of 226.9 per 100,000 is still nearly 50% above the national median of 152.2, and gonorrhea is nearly 43% higher than it was in 2008. Syphilis tells a sharper story. The rate has almost tripled since 2008 — up 197.9% over that span — and jumped another 21.7% just between 2022 and 2023. At 28.6 per 100,000, it's nearly double the national median of 14.8.

Alabama's HIV data, available through 2022, shows a persistent and rising case count. New diagnoses climbed from 593 in 2020 to 689 in 2022 — the highest in the six-year window. The 2020 dip almost certainly reflects pandemic-era disruptions to testing, not an actual reduction in transmission. HIV rates are highest in metro areas, which puts Birmingham, Montgomery, and Huntsville at the center of the state's testing need. If you live in or near any of these cities, STDTest.com can help you find a nearby testing location.

STD Trends in Alabama

Chlamydia
651.1
per 100,000 • 33,261 cases
6.4 from 2022
22.9 since 2008

Alabama's chlamydia rate has never really leveled off — it hit a new recent high in 2023 at 651.1 per 100,000, up 6.4% from the year before. That rate sits 38% above the national median, and the long-run climb since 2008 has been steady rather than sudden. The absence of any real plateau is what makes this the state's most persistent STD challenge.

Gonorrhea
226.9
per 100,000 • 11,592 cases
-13.3 from 2022
8.9 since 2008

Gonorrhea dropped 13.3% in Alabama from 2022 to 2023, which is a meaningful shift — but it comes after years of steep increases that pushed the rate far above where it was a decade ago. At 226.9 per 100,000, Alabama is still nearly 50% above the national median of 152.2. The long-run rise since 2008 stands at nearly 9%, and the rate peaked at 321.3 in 2021 before beginning to ease.

Syphilis (P&S)
28.6
per 100,000 • 1,460 cases
21.7 from 2022
197.9 since 2008

Syphilis is Alabama's fastest-moving STD story. The rate has risen nearly 198% since 2008 — from 9.6 to 28.6 per 100,000 — and it climbed another 21.7% in a single year between 2022 and 2023. At nearly double the national median of 14.8, Alabama's syphilis rate reflects a trend that has accelerated sharply over the past five years.

HIV
16.1
per 100,000 • 689 cases

Alabama's HIV data covers 2017 through 2022 and shows a rate that has remained persistently elevated, with new diagnoses ranging between 593 and 689 per year. The 2020 figure — the lowest in the dataset at 593 cases — almost certainly understates actual transmission, as pandemic-related clinic closures and reduced testing suppressed diagnosis counts nationwide. By 2022, the state recorded 689 new cases at a rate of 16.1 per 100,000, the highest point in the six-year window.

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Alabama vs National Average

Comparing 2023 rates against the U.S. median across all 50 states.

Infection Alabama US Median Difference
Chlamydia 651.1 471.3 38.1% above
Gonorrhea 226.9 152.2 49.1% above
Syphilis (P&S) 28.6 14.8 93.2% above

What the numbers mean — and what to do about them

Alabama's combined STD rate of 906.6 per 100,000 people translates to more than 46,000 diagnoses of chlamydia, gonorrhea, and syphilis in a single year — in a state of just over 5 million. That's not an abstraction. It means a significant share of sexually active Alabamians are encountering these infections, and most won't know without getting tested.

The trend that most warrants attention is syphilis. A nearly 200% rise since 2008, followed by a 21.7% jump in just the last year, points to an infection that is spreading faster than awareness of it. Syphilis is also frequently asymptomatic in early stages, which means transmission continues well before anyone seeks treatment. Chlamydia carries the same problem at much higher volume — over 33,000 cases diagnosed in 2023, with the actual number of infections likely higher because undetected cases never enter the count. Alabama's gonorrhea rate dropped last year, but at 226.9 per 100,000 it remains one of the highest in the country. These aren't diseases that announce themselves. That's the core issue.

If you live in Alabama — especially in or around Birmingham, Montgomery, or Huntsville, where STD rates tend to concentrate in urban centers — routine testing is the only reliable way to know your status. Alabama's syphilis rate has nearly tripled since 2008 while most people weren't paying attention. STDTest.com can show you where to get tested today.

WHO SHOULD GET TESTED

Any sexually active adult in Alabama, given the state's 5th-place national ranking for combined STD rates. The risk is especially relevant for people in Birmingham, Montgomery, and Huntsville, where urban transmission rates are highest, and for anyone with a new or multiple partners — since both chlamydia and syphilis are rising and often show no symptoms.

HOW OFTEN

At least once a year for sexually active adults is a reasonable floor given Alabama's elevated rates across all three major STDs. With chlamydia at a recent high and syphilis still climbing, people with multiple partners or inconsistent condom use should consider testing every three to six months. Don't wait for symptoms — most infections in Alabama go unnoticed until a test catches them.

WHAT TO EXPECT

Testing for chlamydia, gonorrhea, and syphilis is quick and straightforward — usually a urine sample or swab, plus a blood draw for syphilis and HIV. Most results come back within a few days. Many clinics in Alabama offer confidential or anonymous testing, and same-day appointments are available at locations across the state.

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FAQs

Alabama's syphilis rate has risen 197.9% since 2008, reaching 28.6 per 100,000 in 2023 — nearly double the national median of 14.8. This long-run increase mirrors a national pattern of syphilis resurgence, but Alabama's rate has accelerated faster than most states. The 21.7% jump from 2022 to 2023 alone suggests the trend is still building rather than stabilizing.
Alabama ranks 5th out of 50 states for combined STD rates in 2023, with a combined rate of 906.6 per 100,000 — about 42% above the US combined median. Its chlamydia rate of 651.1 is 38% above the national median, and its gonorrhea rate of 226.9 is nearly 50% higher than the median. Only four states report a higher per-capita STD burden.
Yes — gonorrhea fell 13.3% from 2022 to 2023 in Alabama, the largest single-year decline in recent data. That said, the rate of 226.9 per 100,000 remains well above the national median of 152.2, and the long-run rate is still higher than it was in 2008. The decline is a shift in direction, but not a return to historically lower levels.
STDTest.com maintains an updated directory of testing locations across Alabama, including clinics in Birmingham, Montgomery, and Huntsville. These three cities carry the largest share of the state's STD caseload. You can search by zip code to find the nearest option, including same-day testing at many locations.
With Alabama ranking 5th nationally for STD rates and chlamydia hitting a new high in 2023, annual testing is a reasonable baseline for sexually active adults — more frequently if you have multiple partners or a new partner. Because chlamydia and gonorrhea are often asymptomatic, many people carry an infection without knowing it. Regular testing is how most cases actually get caught.
Data sourced from the CDC's annual STI Surveillance Report. Rates are per 100,000 population and reflect reported cases only — actual prevalence is likely higher due to undiagnosed infections. While we strive for accuracy, STDTest.com makes no representations or warranties regarding the completeness or accuracy of this data and is not responsible for any errors or omissions. This page is for informational purposes only and does not constitute medical advice.